Cascading flow and multi-organ device, for cells-in-system approaches.
An in vitro cell culture tool that consists of wells linked together through microfluidic channels and a syphon-drive system that controls flow through and between wells. The system allows for a "tempered" flow of chemical concentrations through wells either of a single lineage or between multiple lineages. The device advances nutrient transport for ‘cells in system’ approaches, and was designed to retain traditional culture configurations while advancing fluid distributions with grafted flow paths. This affords users the option to evaluate networked –cell, -tissue, and -environment relationships.
SciKon Innovation is creating human organ systems for the benchtop.
We engage in scientific engineering and construction, with biological relevance. SciKon approaches biotools by embracing a deep understanding of engineering and a love for biology of the human body. Our mission is to produce improved bio-tools for biomedical and pharmaceutical applications by exploiting engineering principles to produce human-relevant cell ecosystems. Specifically, we engineer tools that integrate human cells, tissues, and organs in controlled and modifiable environments. These cell culture systems lead to improved predictive models of the body’s response to toxins, drugs, and medications.
Save Your Cells! Thawing media for cryopreserved cells.
Improve your organization’s cellular systems. KryoThaw, a unique thawing media for cryopreserved cells, can increase cell viability, quality of cell yield, and cell plateability. KryoThaw improves upon the three primary modes of cryopreservation cell decay: physical cell rupture, cell necrosis, and apoptosis. This ready-to-use product simply requires a 1-step centrifugation process. Versions have been optimized for hepatocytes, intestinal cells, and progenitors.
Scientific Construction. Merging engineering and environments in support of biological relevance.
SciKon’s industrial and academic experiences are focused on bioengineered 2D and 3D environment-cell interactions. Our involvement includes human tissue procurement, primary cell development, bioreactor culture pharmaceutical trials, cryopreservation and cell thaw technology, and native “single organ” and “multi organ” in vitro co-culture systems. We amend mother natures’ native microenvironment design for the in vitro maintenance of cell health.
Human Hepatitis B virus models using Pekin Ducks.
Due to the narrow host range of hepatitis B virus (HBV) that infects humans, the closely related duck HBV (DHBV) provides a useful model in the hepadnavirus life cycle, virus-host interactions, and antiviral strategies.

Biotools to re-create the body’s response to disease.