Study Exposure Examples

Acetaminophen (APAP), Cell Viability in Real-Time This study outlines the use of SciFlow 1000 and is focused on measuring APAP effects. Literature shows APAP is metabolized to a toxic intermediate, and under prolonged incubations result in toxicity and cell death. In the SciFlow System, cell metabolite ratios will increase in wells furthest from the dosing well (i.e. wells 6-11) after the parent compound (e.g. APAP) is infused into the dosing well (well-1). It is intended for assessing cytotoxicity in cell culture, in each of the 9 interconnected cellular compartments of the SciFlow system. Details relate to kinetic studies involving multiple plate measurements over a time course. To access Click Here